Marylynn Snyder , Ph.D.
Assistant Professor
Department of Biological Sciences
(973) 275-2113
Email
McNulty Hall
Room 417
Marylynn Snyder, Ph.D.
Assistant Professor
Department of Biological Sciences
Marylynn Snyder, Ph.D. joined the Department of Biological Sciences at Seton Hall University in 2020 and has taught Introduction to Microbiology, Molecular Biology, Graduate Molecular Biology, Genetics, Cancer Biology and Senior Biology Seminar. She completed her Ph.D. at Rutgers-Graduate School of Biomedical Sciences where her thesis focused on eukaryotic DNA replication using the budding yeast Saccharomyces cerevisiae as a model system. Snyder's postdoctoral training was completed at Weill Cornell Medical College, where her research focused on transcriptional regulation by the JAK-STAT signaling pathway in the processes of stem cell differentiation and breast cancer metastasis.
Education
- Ph.D., Rutgers-Graduate School of Biomedical Sciences
- B.S., Felician University and Rutgers-School of Health Professions
Scholarship
- Snyder, M., He, W., Zhang, J.J. (2005) The DNA Replication Factor MCM5 is Essential
for Stat1-Mediated Transcriptional Activation. Proceedings of the National Academy of Sciences USA. 102 (41): 14539-14544.
- Sun, W., Xu, W., Snyder, M., He, W., Ho, H., Ivashkiv, L.B., Zhang, J.J. (2005) The
Conserved Leu-724 Residue is Required for Both Serine Phosphorylation and Co-Activator
Recruitment for Stat1-Mediated Transcription Activation in Response to IFN-y. The Journal of Biological Chemistry. 280 (51): 41844-41851.
- Sun, W., Snyder, M., Levy, D.E., Zhang, J.J. (2006) Regulation of Stat3 Transcriptional Activity
by the Conserved LPMSP Motif for OSM and IL-6 Signaling. FEBS Letters. 580: 5880-5884.
- Dershowitz, A., Snyder, M., Sbia, M., Skurnick, J.H., Ong, L.Y., Newlon, C.S. (2007) Linear
Derivatives Of Saccharomyces cerevisiae Chromosome III Can Be Maintained in the Absence
of Autonomously Replicating Sequence Elements. Molecular and Cellular Biology. 27: 4652-4663.
- Snyder, M., Huang, X.-Y., Zhang, J.J. (2008) Identification of Novel Direct Stat3
Target Genes for Control of Growth and Differentiation. The Journal of Biological Chemistry. 283: 3791-3798.
- Snyder, M., Huang, X.-Y., Zhang, J.J. (2009) The Minichromosome Maintenance Proteins 2-7
(MCM2-7) are Necessary for RNA Polymerase II (Pol II)-Mediated Transcription. The Journal of Biological Chemistry. 284:13466-13472.
- Snyder, M., Huang, X.-Y., Zhang, J.J. (2010) Stat3 Directly Controls the Expression
of Tbx5, Nkx2.5, and GATA4 and is Essential for Cardiomyocyte Differentiation of P19CL6
Cells. The Journal of Biological Chemistry. 285: 23639-23646.
- Snyder, M., Huang, X.-Y., Zhang, J.J. (2011) Stat3 is Essential for Neuronal Differentiation Through
Direct Transcriptional Regulation of the Sox6 Gene. FEBS Letters. 585: 148-152.
- Snyder, M., Huang, X.-Y., Zhang, J.J. (2011) Signal Transducers and Activators of Transcription
3 (STAT3) Directly Regulates Cytokine-Induced Fascin Expression and is Required for
Breast Cancer Cell Migration. The Journal of Biological Chemistry. 286: 38886-38893.
- Snyder, M., Huang, J., Huang, X.-Y., Zhang, J.J. (2014) A Signal Transducer and
Activator of Transcription 3-Nuclear Factor kB (Stat3/NFkB) Complex is Necessary for the Expression of Fascin in Metastatic Breast Cancer Cells
in Response to Interleukin(IL)-6 and Tumor Necrosis Factor (TNF)-α. The Journal of Biological Chemistry. 289: 30082-30089.
- Zhang, W., Qu, X., Chen, B., Snyder, M., Wang, M., Li, B, Tang, Y, Chen, H., Zhu,
W., Zhan, L., Yin, N., Li, D, Xie, L., Liu, Y, Zhang, J., Fu, X.-Y., Rubart-von der
Lohe, M., Song, L.-S., Huang, X.-Y., and Shou, W. (2016). Critical Roles of STAT3
in beta-Adrenergic Functions in the Heart. Circulation. 133: 48-61.
- Govindasamy, K, Khan, R., Snyder, M., Lou, H., Du, P., Kudyba, H., Muralidharan, V., Turk, B., and Bhanot, P. (2018) Plasmodium falciparum cGMP-dependent protein kinase interacts with a subunit of the parasite proteasome. Infection and Immunity. 87(1): 1-13.